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Yamamoto, H., & Murphy, L.J

Acute Kidney Injury Acute kidney injury is a rapid impairment of renal function that occurs in a matter of hours or days

Graded regulation of cellular quiescence depth between proliferation and senescence by a lysosomal dimmer switch

Its not simply the kidneys "slowing down", its a multifaceted process involving: Chronic inflammation Fibrosis (scar tissue replacing healthy kidney cells) Vascular damage Autoimmune triggers Oxidative stress Reduced regenerative capacity Until now, the primary goal of treatment has been preservation, not restoration

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