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For a total calorie intake of 4000 kcal, this amounts to around 570 calories per meal (or 666 kcal with six meals)

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Although mechanisms other than hyperglycemia are known to contribute to the development and severity of DPN (42,43), recent research has shown that some antidiabetic drugs and the long-term maintenance of healthy blood glucose concentrations can contribute to improvements in DPN-related symptoms in at least some patients (44,45)