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The goal of Sermorelin therapy is not to create artificial hormone spikes, but rather to support healthier natural hormone signaling over time

While proteins are long, complex molecules made up of 50 or more amino acids, peptides are much shorter

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Excluding one participant with ASD who did not fast on the day of the MRS scan did not materially alter the results (please note that neurometabolite measures in the thalamus of this participant were already excluded by our quality check)

Participants who switched from tirzepatide to placebo after 36 weeks of treatment regained substantial weight, while those who continued tirzepatide maintained their weight loss and continued losing