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A major difference between the two peptides appears to be their respective half-lives, where the half-life of Sermorelin is considered to be 11 to 12 minutes and that of Ipamorelin is approximately 2 hours

PMID: 21896138 Sido B, Braunstein J, Breitkreutz R, Herfarth C, Meuer SC

Mitigating the effects of external and environmental sources of oxidative stress on sperm requires a multifaceted approach