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Enucleation, a rate-limiting step of erythrocyte maturation, is tightly regulated via coordination of multiple transcription factors (FOXO3, E2F2, etc.), miRNAs (miR-30a, miR-191, miR-181a), cytoskeleton proteins (F-actin, dynein, tropomodulin, etc.), and kinases (p38 MAPK, p38 mitogen-activated protein kinase) [33]

Each technique reveals complementary data, contributing to a holistic understanding of GHK-Cu

Lyophilized primers were resuspended in TE buffer (1 M Tris, 0.5 M EDTA) upon arrival and diluted 1:10 in sterile water to create a 10 M working solution

For both clearance and proliferation, macrophages that are recruited to the damaged area play an important role

F.LuZ.LuF.et al (2021b)