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Oral Contraceptives and Hormone Therapies The gastric-emptying delay caused by GLP-1 medications can reduce the effectiveness of oral contraceptives, particularly with tirzepatide (Mounjaro/Zepbound)

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Water, Water, Water: Drink at least 1620 ounces of water 3060 minutes before your first drink

According to the Summaries of Product Characteristics (SmPCs), nausea is very common with most GLP-1 medications, while abdominal distension, eructation (belching), and flatulence are typically classified as common side effects, though frequencies differ between products