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The 'Long R3' modification extends IGF-1 half-life from 10 minutes to 2030 hours by reducing IGF-binding protein affinity 100-fold, creating sustained anabolic signalling endogenous IGF-1 cannot match

10.1016/j.molmet.2016.05.012 28 GuoS.Al-SadiR.SaidH

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Studies have suggested that GLP-1 receptor agonists might have neuroprotective effects

Penetration of short fluorescence-labeled peptides into the nucleus in HeLa cells and in vitro specific interaction of the peptides with deoxyribonucleotides and DNA