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Nevertheless, more diverse vaginal microbiomes have been observed globally across different healthy populations (North America 146 , Scandinavia 147 , South Africa 148 , and Kenya 149 ), but are usually associated with adverse sexual and reproductive outcomes 150

Small molecule modulation of signaling pathways (e.g., Wnt, TGF-beta, HGF) and epigenetic profiles can promote the differentiation of stem cells into hepatocyte-like cells or direct reprogramming of fibroblasts into hepatocytes

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Oxidative stress is recognized as a major pathogenic mechanism in PD

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