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2023 NEJM) randomized 17,604 adults with overweight or obesity and established cardiovascular disease (without diabetes) to semaglutide 2.4 mg weekly or placebo

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The authors hypothesized that early life adversity may alter oral microbiome composition, which can shift to gut via saliva, potentially creating a pro-inflammatory state that increases vulnerability to PTSD following subsequent trauma exposure (Malan-Muller et al., 2022)

Together, they became my healing pit crew, patching up years of wear and tear from swimming, surfing, and life in general