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Jorsal T, Rhee NA, Pedersen J, Wahlgren CD, Mortensen B, Jepsen SL, et al

The practical implication: if you have a history of gastroparesis or symptoms suggesting poor gastric emptying (persistent nausea, chronic bloating, vomiting of undigested food hours after eating), this needs to be discussed with your doctor before starting tirzepatide or during any dose increase

However, the lack of efficacy in the active control group treated with rasagiline raises question on possible issues with study design and conduct (Hauser et al

Your doctor will review your full history at intake

Semaglutide is unchanged: Mira's previous August 2024 review reported $299 per month, and Willow still advertises $299 in July 2026