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NRF2 inducers, like sulforaphane modify cysteine sensors of Keap1 and inactivate its repressor function

According to the World Health Organization and the International Committee for Monitoring Assisted Reproductive Technology, infertility is a reproductive system disease defined as the failure to achieve clinical pregnancy after 12 months or more of routine unprotected sex ( via semen analysis, including determination of the sperm concentration/total number, motility, and morphology ( Genetic abnormalities can lead to spermatogenic disorders and account for 1530% of male infertility ( Chemical elements play important roles in male reproduction because imbalance of micronutrients or macronutrients may lead to spermatogenesis defects and decreased libido, resulting in male infertility

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