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Neither approaches the efficacy or tolerability of modern GLP-1 based treatments

The latter is a competitor of 2-Oxoglutarate-dependent dioxygenases such as Ten-eleven translocation methylcytosine dioxygenase and therefore induces DNA hydroxymethylation and gene upregulation 52

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Most DHEA is sulfated before being released into the bloodstream and circulates as DHEA-sulfate (DHEA-S)

Furthermore, ongoing research explores the structural basis of KPV's antifungal effects, suggesting its potential as a structural model for the development of novel antifungal research compounds with improved activity and selectivity