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The p53 pathway inhibitor pifithrin- (PFT-) ( Anti-inflammatory drugs Neuroinflammation has been demonstrated to inhibit neurogenesis and the presence of various inflammatory components, such as immune cells, cytokines, or chemokines, plays a role in regulating the survival, proliferation, and maturation of NSCs (80)

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Alternatively, CRISPR/Cas13 (e.g., CasRx or Cas13d) could be employed to specifically degrade YTHDF1 mRNA or even directly target SLC7A5 mRNA for degradation, offering more robust genetic evidence for the YTHDF1-SLC7A5 axis in PCOS-related ferroptosis

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