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Potential Side Effects While Vitamin B12 injections are generally safe, some people may experience mild side effects, including: Pain or redness at the injection site Mild diarrhea Itching or rash Headache Dizziness Severe allergic reactions are rare but require immediate medical attention

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Strong AP, Haeusler S, Weatherall M, Krebs J (2016) Sublingual vitamin B12 compared to intramuscular injection in patients with type 2 diabetes treated with metformin: a randomized trial

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Iron chelating agent DFP is commonly used in the treatment of thalassemia syndrome patients, effectively reducing serum ferritin, and increasing transferrin saturation, and is well-tolerated