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While the overall risk of jaundice from semaglutide remains low, close monitoring and careful medical review are important when these risk factors are present

Similarly, patients with active malignancy warrant careful consideration given theoretical concerns about angiogenic effects potentially affecting tumor growth, though preclinical evidence suggests context-dependent effects that may inhibit rather than promote tumor angiogenesis

Handling: Always utilize strict aseptic laboratory techniques to prevent bacterial or fungal contamination of the vial

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