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Disease management involves a multidisciplinary approach, including lifestyle modifications, medication, and specialized care (Rossing et al., 2022)

Despite the absence of a statistically significant doseresponse relationship observed in this analysis, clinical decision-making should consider that absorption efficiencyrather than absolute dosagemay be the limiting factor

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Structurally, all statins share a similar pharmacophore with the HMG-CR moiety as shown in Figure 2 (Schachter, 2005)

Nature (2012) 485:2425.10.1038/nature11011 12 SandersSJMurthaMTGuptaARMurdochJDRaubesonMJWillseyAJet alDe novo mutations revealed by whole-exome sequencing are strongly associated with autism