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We found that the receptor doesnt just signal at the cell surface, it moves inside the cell to form a specialised hub at ER contact sites

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In humans, L585 cleavage by CPA reduces the plasma half-life of albumin from 3 weeks to 3.5 days due to loss of FcRn binding affinity 60

Both peptides are used in biohacker protocols based entirely on extrapolated animal dosesa significant leap given the translation challenges seen with other compounds