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Researchers have investigated this compound as a tool for modulating NNMT activity in in vitro and preclinical models, providing insight into the enzyme's role in metabolic homeostasis

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(2016) summarized decades of BPC-157 research in the brain-gut axis context, describing interactions with dopaminergic (D2), serotonergic, GABAergic, and opioid pathways in animal models [10]

In December 2024 tirzepatide was approved by the FDA for the treatment of moderate to severe obstructive sleep apnea in adults with obesity