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Recently, observational data have raised questions about a possible association between semaglutide, a GLP-1 receptor agonist used for diabetes and weight management, and NAION

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In major clinical trials, such as the landmark STEP 1 trial published in the New England Journal of Medicine , a once-weekly injection of semaglutide 2.4 mg resulted in an average body weight reduction of roughly 14.9% over 68 weeks