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Administrative claims data, which are primarily used for billing, may contain diagnostic or treatment inaccuracies due to coding errors or undocumented medication use and exclude free samples and over-the-counter drugs

Because the kidneys clear the drug, reduced kidney function raises the risk of complications

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Acknowledgments We thank Bojana Mircetic for language editing

In PsA, the phase 3b TOGETHER-PsA trial (NCT06588296) assesses the combined use of ixekizumab and tirzepatide in patients with active disease and concomitant overweight or obesity, while the phase 4 TOGETHER AMPLIFY-PsA study (NCT06864026) examines the effectiveness of adding tirzepatide to ixekizumab in clinical practice over 12 months