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Another consideration is their shelf life after opening

Another form of renal toxicity, generally associated with NSAIDs, is seen in patients with prerenal conditions leading to the reduction in renal blood flow or blood volume, where the renal prostaglandins have a supportive role in maintaining renal perfusion

[ 1 , 2 ] The peptide consisted of nine amino acids and was named delta sleep-inducing peptide because of its apparent ability to enhance delta-wave activity, a characteristic feature of deep non-rapid eye movement (NREM) sleep

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Possibilities include: fecal SCFA levels (as an indicator of beneficial fermentation), serum TMAO (marker of detrimental microbial metabolism), gut permeability assays (like urinary sugar tests or blood zonulin) to gauge gut barrier integrity, and even gut microbial gene profiles that might predict rapid vs slow disease progression