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Indeed, rats selectively bred for low intrinsic aerobic capacity display decreased mitochondrial FAO and were predisposed to diet-induced hepatic steatosis [95]

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The majority of people who carry the mutations are from the tropical and subtropical regions of Africa, India, SE Asia, the Middle East, and Mediterranean regions like Sardinia.[ref][ref][ref] One key that I want to emphasize is that the different mutations that cause G6PD deficiency cause different reductions in enzyme function