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Indeed, several gastrointestinal hormones such as cholecystokinin (CCK), peptide YY, and glucagon-like peptide 1 (GLP-1), transmit orexigenic and satiating signals to the brain, at least in part, via vagal afferents [198,199,200]

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Activation of these pathways will control transcription programs that are responsible for cellular proliferation, differentiation, protein synthesis and survival signals

The EU's Scientific Committee on Consumer Safety (SCCS) said the mouse findings might point to a concern but they're hard to apply to humans since hairless mouse skin and human skin behave differently

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