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When to contact your GP: Persistent or severe nausea/vomiting preventing adequate fluid intake Severe, persistent abdominal pain which could indicate pancreatitis New or worsening depression, anxiety, or suicidal thoughts Severe headaches or visual disturbances Unexplained cognitive changes or confusion Signs of hypoglycaemia (if taking alongside insulin or sulfonylureas) NICE guidance recommends regular monitoring during GLP-1 receptor agonist therapy

Not approved by the FDA

Every 10C increase in temperature doubles the degradation rate

If abnormal TSH levels persist, Ill ask my clients to speak with their doctor about thyroid hormone treatment

The findings have been comprehensively reviewed in our previous publication [81]