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Fatigue is a common complaint during the early weeks of GLP-1 treatment, particularly as calorie intake drops and the body adjusts to lower food volume

As a fragment of growth hormone that specifically targets fat metabolism, it appears to avoid many of the side effects associated with full growth hormone therapy, such as joint pain, fluid retention, and effects on glucose metabolism

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Sirtuins are a family of NAD + -dependent deacylases that have been shown to regulate a myriad of biological functions, ranging from cell growth to lifespan extension, including oxidative stress, DNA damage, glycolysis, gluconeogenesis, and lipogenesis [1316]

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