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So rather than seeing it as simply about too much sugar, its about ensuring the system never reaches that overflow point by lowering unnecessary glucose load and helping the mitochondria run on fuels they handle better

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Ingram DK, Chefer S, Matochik J, Moscrip TD, Weed J, Roth GS, Londonb ED, Lane MA (2001) Aging and caloric restriction in nonhuman primates: behavioral and in vivo brain imaging studies

In clinical trials at the 12 mg dose, researchers documented nausea in 28% of participants, diarrhea in 23%, constipation in 17%, and vomiting in 12%

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