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TISSUE-SPECIFIC ANDROGEN RECEPTOR MEDIATED ACTIONS IN MOUSE MODELS Genetic mouse models in which the androgen receptor gene has been inactivated (so-called ARKO [androgen receptor knock-out] mouse models) are valuable tools to understand in detail the role of receptor-mediated pathways in male and female reproductive functions

Mouse research reported antinociceptive responses following central administration of DSIP

An interim analysis of a phase II study (FLIGHT-FXR) in biopsy-proven NASH patients with significant fibrosis (defined as stage 23 fibrosis) exhibited significant efficacy of tropifexor in hepatic steatosis reduction at 12 weeks after treatment