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Ngan HY, Chong YY, Chien WT

5.2.2 Key antioxidant pathways in ferroptosis regulation Vitexin, a flavonoid monomer extracted from hawthorn leaves, mung bean peels, and other plants, demonstrates pharmacological effects in reducing ROS and RNS levels

Once synthesized, GSH serves as a substrate for GSH peroxidases (GPx), which reduce hydrogen peroxide and lipid peroxides into water and lipid alcohols, respectively ( The glutaredoxin (Grx) system, another key player, operates in close association with the GSH pool and serves primarily to regulate protein thiol redox status through reversible de-glutathionylation

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Yes, with important qualification