These treatments can help restore a more youthful appearance, boosting self-confidence and self-image
1 In June 2025, the MHRA reinforced this in a public safety update, advising that GLP-1 medicines (a class of weight management and diabetes medications that includes Mounjaro, Wegovy, and Ozempic) must not be taken during pregnancy, while trying to get pregnant, or during breastfeeding
Physical activity accelerates visible results but doesn't drive initial weight loss
Gene therapy may increase cancer risk [153,154,155]
However, further research is needed to fully understand how these therapies exert their effect on body weight and in the last section we cover open questions about the potential mechanisms of multiagonist drugs, and the understanding of how gutbrain communication can be leveraged to achieve sustained body weight loss without adverse effects