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TJ protein disruption, neuroinflammation, oxidative stress, and ROS production are fundamental mechanisms through which drugs alter the BBB structure and integrity

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In this work, we construct a multiple hydrogen-bond crosslinked hydrogel loaded with tannic acid and Kartogenin by polyaddition reaction as a cell-free scaffold for in vivo cartilage regeneration, which features ultra-durable mechanical properties and stage-dependent drug release behavior

The characteristics of Glutathione Beads are summarized in Table

-thalassaemia major results in ineffective haemoglobin synthesis that requires chronic red blood cell transfusions, which might result in iatrogenic iron accumulation, hypogonadism and/or aberrant spermatogenesis