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Track waist circumference, progress photos, how clothing fits, energy levels throughout the day, sleep quality, blood work improvements (A1C, lipids, liver enzymes), and appetite patterns and food relationships

Nat Immunol 25 , 13321343 (2024)

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Clinical trials have shown it produces somewhat larger average weight loss than semaglutide alone, which may be relevant for adults over 50 who have more metabolic resistance to overcome