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The results indicated that EGCG accounted for approximately 73 wt% of the nanocomplex, while zinc accounted for approximately 28 wt%, corresponding to a Zn/EGCG mass ratio of approximately 1:4 and a molar ratio close to 1:3

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The prepared topical formulation exhibited prolonged drug release patterns ( 6.4 Transfersomes Transfersomes are biocompatible vesicular nanocarriers with high deformability potential that are composed of lipids bilayer and membrane softeners (Hatem et al., 2018)

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