amino tirzepatide Tirzepatide | GLP-1R and GIPR

Many people describe the drugs effects not simply as appetite suppression, but as a quieting of persistent food noise. But as clinical trials expand and preclinical research continues, evidence is accumulating that these medications exert much broader physiological effects than previously thought

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GLP-1 receptor agonists pass the bloodbrain barrier and directly engage with GLP-1 receptors in essential appetite-regulating sites of the hypothalamus and brainstem (Trapp and Brierley 2022)

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When PT-141 binds to MC4R, it stimulates the release of neurochemicals involved in sexual responses, such as dopamine