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Moreover, low antioxidative enzyme activity (CAT, SOD, glutathione reductase (GR), and glutathione peroxidase (GPx) levels) and increased nitric oxide (NO) and MDA (a marker of lipid peroxidation (LPO)) in red blood cell lysate are observed in FM subjects

There will need to be an adjustment to account for additional costs

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For example, hyperhomocysteinemia (linked to gut microbial metabolism) can alter DNA methylation in the brain and has been associated with increased AD pathology [114]