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Among them, capsaicin (8-methyl N-vanillyl-6-noneamide, CAP), as a key active component of peppers, has been shown to have potential therapeutic effects on central nervous system (CNS) diseases such as Parkinsons disease, epilepsy, and depression

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Wang X, Sun K, Dong J, Ge Y, Liu H, Jin X et al (2025) Carrier-free nanoparticles based on natural products trigger dual synergy and attenuation for enhanced phototherapy of liver cancer

Activation of MC1R in skin drives melanin synthesis (tanning), while central MC3R/MC4R activity is linked to its libido and appetite effects [5]

What Do Absorption Kinetics Tell Us About Each Route