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Reasons patients choose to have a lipoma removed Cosmetic appearance visible lipomas on the neck, shoulder, arm, face or scalp that the patient does not want to live with Mechanical discomfort lipomas that catch on clothing, sit under a bra strap, rub against a watch or belt, or interfere with sleep Tenderness angiolipomas in particular can be painful to pressure even when small Functional limitation large lipomas in the armpit, groin or behind a joint can restrict movement Diagnostic certainty some patients prefer a definitive histopathology diagnosis rather than continuing to monitor an undiagnosed lump When removal is clinically advised There are some lipomas where removal is more strongly indicated rather than purely cosmetic: Rapidly growing lipomas (more than a centimetre over a few months) Lipomas that have suddenly become painful Lipomas that feel firm or hard to the touch Lipomas larger than 5cm Lipomas that sit deep within or below muscle These features can rarely indicate liposarcoma a malignant tumour of fat cells that is a different condition from a lipoma but can look superficially similar

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Best Pract Res Clin Obstet Gynaecol 18:707718 Pietro M, Pascuali N, Parborell F, Abramovich D (2018) Ovarian angiogenesis in polycystic ovary syndrome