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Humans have not shown the same risk, but people with a family history of thyroid cancer or MEN 2 (a rare condition) should avoid these drugs
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The European Medicines Agency (EMA) is separately reviewing a Marketing Authorisation Application for apitegromab for the treatment of spinal muscular atrophy (SMA), an unrelated neuromuscular condition, with a decision anticipated in mid-to-late 2026
For diabetes, retatrutide appears to help by improving the bodys hormone response to food, especially through GLP-1 and GIP, which support insulin release when glucose is high
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