Glutathione, often called the body's master antioxidant, plays a key role in detoxification by binding to a wide variety of toxins and helping remove them from the body
[ref] The glutamate-cysteine ligase (GCL) enzyme interacts with glutamate and cysteine, resulting in the formation of gamma-glutamylcysteine
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Cross-sectional studies have shown that plasma and tissue glutathione concentrations decrease by approximately 10-15% per decade after age 45, and this decline is accelerated in conditions associated with chronic oxidative stress, including type 2 diabetes, cardiovascular disease, neurodegenerative diseases, HIV/AIDS, chronic liver disease, and chronic obstructive pulmonary disease (COPD) [2][3][10][11]
Effect of glutathione, catechin, and epicatechin on the survival of Drosophila melanogaster under paraquat treatment