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Copper overload risk is theoretical

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Candidate diagnostic biomarkers for neurodevelopmental disorders in children and adolescents: a systematic review

They have also reported noticeable improvements in mental focus

Bioactivation of 6,7-dimethyl-2,4-di-1-pyrrolidinyl-7h-pyrrolo[2,3-d]pyrimidine (U-89843) to reactive intermediates that bind covalently to macromolecules and produce genotoxicity