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Description

Masip, L., Veeravalli, K., & Georgiou, G

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, Di Liegro C

First, we accentuate the bidirectional vicious cycle between -syn aggregation and ferroptosis, elaborating not only on how -syn disrupts iron homeostasis and drives lipid peroxidation, but also how iron and its associated oxidative metabolites directly stabilize -syn oligomers and accelerate fibrillation