There is evidence that metformin can increase the abundance of microbiota which can all produce SCFAs such as Butyrivibrio , Bifidobacterium , Megasphaera , Prevotella , and so on (de la Cuesta-Zuluaga et al., 2017)
Habotta O, Ateya A, Saleh RM, El-Ashry ES (2023) Thiamethoxam evoked neural oxido-inflammatory stress in male rats through modulation of Nrf2/NF-kB/iNOS signaling and inflammatory cytokines: neuroprotective effect of Silymarin
Via the integration of GST inhibitor screening, enzyme inhibition kinetics, and molecular modeling approaches, they identified that 2,2-dihydroxybenzophenones 6 and 8, as well as the N-acyl hydrazone analogues 14 and 16, exhibited satisfactory inhibitory potencies (IC 50(6) = 1.77 0.10 M
The orange spectra are those acquired from the TDC group, while the green spectra are those acquired from the ASD group
That was my big question too when I started my weight loss journey