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Animals were kept in laboratory for 3-4 days for acclimatization, with free access to food and water

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The severity of periodontitis is evaluated through clinical indicators such as periodontal pocket depth and the gingival bleeding index, while also incorporating the diversity and degree of dysbiosis within the oral microbiota to inform treatment decisions

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PKD1 inhibits AMPK2 through phosphorylation of serine 491 and impairs insulin signaling in skeletal muscle cells J biol chem

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