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Glutathione S transferase (GST) is the main intracellular antioxidant synthetized by Glutamate-Cysteine ligase and glutathione synthase, as demonstrated by Chen et al., 2007 in a study including with Gclc Knockout mice, which developed steatosis in very early ages [65]

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Additionally, the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and fibroblast growth factor 21 receptor (FG21R) significantly impact these metabolic processes