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References van Gorkom BA, Karrenbeld A, van Der Sluis T, Koudstaal J, de Vries EG, Kleibeuker JH (2000) Influence of a highly purified senna extract on colonic epithelium

Mutations in GNE lead to the neuromuscular disorder, GNE myopathy, characterized by muscle weakness and atrophy, with protein aggregation seen in muscle biopsy samples 3

Age, hormonal status, sleep quality, and stress levels also modulate how quickly your body mobilizes stored fat