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In summary, VAX-D shows promising results in reducing pain and nerve compression in some patients, but it also carries possible risks

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Collectively, these findings suggest GLP-1RAs may serve as dual-purpose agents by targeting both metabolic and inflammatory components of asthma by modulating arginine metabolism, reducing oxidative stress, preserving lung epithelial integrity, and counteracting inflammation-driven lung injury, with potential mechanistic insight shown in Fig

In addition, these data are completely in line with the effects obtained in hypertensive rats with renal artery stenosis and/or unilateral nephrectomy