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It might sound strange at first that a diabetes and weight loss drug has the potential to treat addiction disorders, but observations from researchers have led to emerging data, anecdotal reports, and pharmacoepidemiologic findings that suggest GLP-1 drugs could be effective for addiction by reducing drug use and craving through the modulation of reward pathways, stress responses, and cognitive functions

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Specifically, they regulate inflammatory responses such as NF-B activation, the proliferation of T-cells, expression of adhesion molecules, inflammatory cytokines, chemokine receptors, and inflammatory cell migration [2]

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2 After 18 months, the WL, WL + AT, and WL + RT groups achieved weight reductions of 5.7 kg, 9.9 kg, and 10.1 kg, respectively