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Here, we summarize that activation of GLP-1 receptor (GLP-1R) suppresses food intake and induces postsynaptic depolarization of membrane potential and/or presynaptic modulation of glutamatergic or GABAergic neurotransmission in brain nuclei located within the medulla oblongata, pons, mesencephalon, diencephalon, and telencephalon

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Figure 1 Collectively, these data show that acute liraglutide treatment significantly improves glucose tolerance, insulin sensitivity and impaired hepatic gluconeogenesis in SKO mice, with the greatest effects being observed in female SKO mice

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