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found that L-carnitine could decrease body weight and BMI because the end product of beta-oxidation, acetyl coenzyme A, can be increased by L-carnitine, which can affect the supply of glucose to brain, thereby regulating energy expenditure and suppressing appetite and could effect on body weight

Top, superimposition of the GLP-1-bound (orange), PF 06882961-bound (pale green) and OWL-833-bound (pale blue) GLP-1R:G s complexes reveal identical backbone conformations within the intracellular portion of the TM bundle, the G protein and the G protein: receptor interface

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[PMC free article: PMC3413200] [PubMed: 22862945] 826