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By sequestering actin and releasing it to fuel lamellipodia extension, TB-500 accelerates the physical migration of keratinocytes and fibroblasts into the repair zone, increasing migration speed by 2-3 fold

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119 CRM hydroxycitrate has been found to stimulate autophagy in U2OS osteosarcoma cells in vitro, thereby increasing antitumor immunosurveillance and reducing tumor mass in mice with autophagy-competent mutant KRAS-induced lung cancers