Analytical rigor was ensured through LC-MS/MS with isotopically labeled standards, enabling precise quantification of TMA and TMAO across biofluids ( in vitro assays with purified TMA lyase (CutC/D) to clarify inhibition kinetics
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The precursor-versus-direct distinction sits underneath this argument
Increased tyrosine hydroxylase (TH) expression accompanied increased dopamine in the striatum of Parkinsonian rats after STN stimulation [367, 368]
Cordido F, Pealva A, Dieguez C, Casanueva FF